Unipro UGENE 64-bit is a free visual software solution for DNA and protein sequence analysis. UGENE provides customizable tools for visualization, analysis, annotation of genetic sequences. Key features are: Integrated MUSCLE alignment tool, Integrated HMMER2 package, OpenGL viewer for PDB macromolecular structures, and Workflow Designer to create and execute custom computational workflows.

Unipro UGENE 64-bit is a free visual software solution for DNA and protein sequence analysis. UGENE provides customizable tools for visualization, analysis, annotation of genetic sequences.

Features:

Integrated tools
Multiple sequence alignment using MUSCLE 3, KAlign, Clustal;
HMM profiles build and search, based on the source of HMMER 2 and HMMER 3;
PCR Primers design using Primer 3;
Cloning in silico capabilities;
Queries to NCBI BLAST and CDD databases;
Protein secondary structure prediction using GOR IV and PSIPRED;
Phylogenetic analysis with Phylip;
Search for restriction enzymes and integration with REBASE;
Extremely fast repeat finder;
DNA short reads to reference alignment using Bowtie;
De novo assembly with CAP3;
Search for transcription factor binding sites using SITECON;
Protein back translation;
ORF finder;
Complete Smith-Waterman algorithm implementation;
Support for external tools: BLAST+, MAFFT, T-Coffee;
Assembly Browser — a shiny BAM viewer.

User interface
Visual and interactive genome browsing including circular plasmid view;
Multiple alignment editor;
Chromatograms visualization;
3D viewer for files in PDB and MMDB formats with anaglyph stereo mode support;
Phylogenetic tree viewer;
Dot plot visualization;
Query designer enables search for complex annotation patterns;
Easy to use workflow designer for custom computational workflows.

High performance computing in UGENE
Complete support of modern multicore processors and SSE instructions;
Out of the box support of modern GPUs using NVIDIA CUDA and ATI Stream;
Support for cloud computing: running computational tasks on Amazon EC2 cloud;
Support for supercomputers and distributed computing.

Cooperation
Can be used for education purposes in schools and universities;
Features to be included into the next release are initiated by users;
UGENE team is ready for collaboration in related projects, both free or commercial

New Release
Adding the UGENE launch shortcut on the Desktop:
Pay attention to the appeared «Create desktop shortcut» button in the «Help» menu.
The «Copy annotations» function is improved in the sequence view:
Copying of selected annotated sequences is tied to the strand of the sequence the current annotation is located on. If there are several annotations on both direct and complementary strands are selected, clicking the «Copy» button causes the copying of sequences from the corresponding strands.
Other improvements:
MySQL 8 is supported.
Phylogenetic trees visualization is improved.
[ Unipro UGENE 64-bit release history ]

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